Tissue Lysates
Cayman Chemical C16 dIhydro CeramIded18 01 1mg
A precursor in the de novo synthesis of C16 ceramide; inhibits C16 ceramide-induced membrane permeabilization in rat liver mitochondria and channel formation in liposomes; biologically inactive as a single agent
Cayman Chemical SynthetIc KhasInIn 1mg
A steroidal glycoside with diverse biological activities; reduces the proliferation of LNCaP and T47D cancer cells (IC50s = 32.1 and 27.5 µM, respectively); inhibits TNF-α-induced nuclear translocation of NF-κB in HaCaT keratinocytes at 50 nM; decreases AST serum levels in a mouse model of carbon tetrachloride-induced liver injury at 0.1 mg/kg; topical administration reduces EAr epidermal thickness and scaling, as well as leukocyte and macrophage infiltration, in an imiquimod-induced mouse model of psoriasis at 5 mg/kg
Cayman Chemical Cholesteryl HomoLInolenate 1mg
A cholesterol ester; accumulates in the adrenal gland of rabbits fed a diet high in linolenic acid; levels are decreased and positively correlate with cognitive decline in HIV-infected humans
Cayman Chemical MDA19 N 5hydroxyhexyl met 1mg
An analytical reference standard that is structurally similar to known synthetic cannabinoids; a potential metabolite of MDA 19 based on the published metabolism of JWH 018; intended for research and forensic applications
Cayman Chemical GnglIosIde GM2bovIn braIn 1mg
A mixture of ganglioside GM2 with C18:1 and C20:1 sphingoid backbones; induces activated T cell death at 150 μg/ml in vitro; serum levels are increased in patients with breast cancer or cholangiocarcinoma; levels are elevated in the brain of patients with Sandhoff disease; accumulates in the lysosomes of individuals with Tay-Sachs disease and GM2-activator deficiency, as well as in the CNS of patients with and animal models of mucopolysaccharide storage disorders and Niemann-Pick disease types A, C1, and C2
Cayman Chemical Latnoprost dImethyl amIde 1mg
A derivative of latanoprost and an isomer of latanoprost ethyl amide
Cayman Chemical 8-Iso ProstaglndIn E2 1mg
8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation.{1943} It is a potent renal vasoconstrictor in the rat.{1943,5157} 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 µM, respectively.{1258} When infused into the renal artery of the rat at a concentration of 4 mg/kg/min, 8-iso PGE2 decreases the GFR and renal plasma flow by 80% without affecting blood pressure.{1943}
American Research Products Inc CELL MITOCHONDRIAL COMPLEX IV
5000265632 CELL MITOCHONDRIAL COMPLEX IV
American Research Products Inc CELL MITOCHONDRIAL COMPLEX I N
5000265747 CELL MITOCHONDRIAL COMPLEX I N
Biolegend Purified anti-UQCRC1
Purified anti-UQCRC1 [O91G2]; Isotype: Mouse IgG1, κ; Reactivity: Human, Mouse; Apps: WB, ICC; Size: 100 μg
FOCUS BIOMOLECULES Biochemical Reagents, Mito-Photo-DNP, Mitochondria specific, photo-activated protonophore, CAS Unknown, 98% by TLC/NMR (Conforms)
Biochemical Reagents, Mito-Photo-DNP, Mitochondria specific, photo-activated protonophore, CAS Unknown, 98% by TLC/NMR (Conforms), Mitochondria-targeted, photo-activated protonophore.1 This novel tool consists of three structural units, a caged protonophore, a photocleavable linker coupled to a triphenylphosphonium moiety which confers selective uptake by the mitochondria.2 Cells are treated with Mito-Photo-DNP at 200 nM and irradiated with UV light at 355 nm. Mito-Photo-DNP can be employed for selective uncoupling of either individual or a small number of mitochondria within a cell when used with fluorescence imaging.1,3
Cayman Chemical MItochondrIal ComP I AcTV 10mL
An MC1R antagonist (IC50 7.23 nM) selective for MC1R over MC2R (IC50 10000 nM) but does antagonize 5-HT2B and 5-HT1A receptors (IC50s 9.66 and 16.9 nM respectively) inhibits MCH-induced [35S]GTPYS binding and calcium influx in HEK293 cells expressing human MC1R at 3 nM reduces stress-induced decreases in the time spent in the open arms of the elevated plus maze in mice at 1 3 and 10 mg/kg decreases immobility time in the forced swim test in mice
Abcam Bovine Heart Mitochondria (ab110338)10mg
Bovine Heart Mitochondria (ab110338)10mg
The product is subject to the following: Abcam Restricted Use Statement